A new study suggests that the anti-depressant drug Viagra could cause a potentially life-threatening heart attack.
Viagra, sold under the brand name Cialis, is the most prescribed medication by doctors to treat erectile dysfunction (ED) in men.
Researchers from University of Michigan's School of Medicine and Health Sciences in Ann Arbor studied the effects of Viagra, a popular brand-name drug that's taken to treat conditions such as ED and heart problems.
Viagra, which was tested in the laboratory for its effectiveness in treating ED, was found to increase the risk of a heart attack, which is the most common type of cardiac arrhythmia seen in men taking nitrates, such as nitroglycerin, and recreational drugs like cocaine or whiskey.
"This is an important finding," said lead study author Dr. Joseph F. Gatto, MD, assistant professor of medicine at Michigan's Michigan State University School of Medicine.
Viagra was originally developed as a heart-healthy alternative to the popular prescription drug Cialis. The drug was first introduced in the late 1980s to treat conditions such as hypertension and angina, but it proved to be an ineffective treatment because the side effects of the drug were so bad that it required hospitalization and the drug's withdrawal in the late 1990s.
"I've had people who've had a heart attack suffer a heart attack come on suddenly," said Gatto, who is now a professor of cardiovascular medicine at Michigan's University of Michigan.
Viagra has been studied extensively in patients with ED and coronary artery disease. The most common side effect is a mild, sudden and severe drop in blood pressure.
Viagra has been found to be effective for the treatment of ED in patients who have cardiovascular risk factors like high blood pressure, high cholesterol and diabetes. Some of the symptoms of ED are:
A study published in the American Journal of Emergency Medicine in June found that men taking Viagra experienced a significant reduction in the number of heart attacks in the first year they used the drug. The number of deaths was also reduced.
More research is needed before scientists can determine if Viagra may be a more effective treatment for ED than other medications such as Cialis or Levitra.
"This is one of the most important findings in our study," Fatto said. "This study suggests that this new study may have implications for other health care treatments."
Cialis was first introduced in the late 1980s to treat erectile dysfunction and had been shown to increase blood flow to the penis. Viagra was found to reduce the risk of a heart attack by more than 40 percent.
Gatto and his colleagues analyzed data from more than 3,300 patients treated with Viagra and found that the drug increased the risk of a heart attack in about 1 percent of the Viagra-treated patients. More research is needed before researchers can determine if Viagra may be a more effective treatment for ED than other medications such as Cialis or Levitra.
Viagra was found to increase the risk of a heart attack by about 30 percent in patients treated with Viagra. The study was published in the September issue ofNew England Journal of Medicine.
In an editorial accompanying the study, Dr. Steven Nissen, MD, director of cardiology at Massachusetts General Hospital, said the new findings suggest that Viagra may be effective for patients who experience ED.
"The new study shows that Viagra may be effective in treating ED and that it is not associated with increased cardiovascular morbidity or mortality," Nissen said.
Gatto said he did not know if Viagra would be the first FDA-approved drug to treat ED in the United States. Viagra is currently only available in generic form. Other ED drugs approved by the FDA include Cialis, Levitra and Staxyn, but these drugs are currently out of reach for many patients.
About one in 10 men who take Viagra will experience a heart attack. That number is expected to increase over time. Because of its effectiveness in treating ED, Viagra has been shown to reduce the risk of heart attacks in some patients.
Although Viagra has been shown to be effective in some patients with ED, Gatto said that was not the case for Viagra in the U. S.
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Quick OverviewAbout Cialis:Cialis is a widely recognized and trusted medication that contains the active ingredient Tadalafil. It is primarily prescribed to help men overcome the challenges of erectile dysfunction (ED), a common condition that can affect intimacy and overall well-being.
How Cialis Works:Cialis works by increasing blood flow to the penis, allowing men to achieve and sustain an erection when sexually stimulated. It is known for its long-lasting effectiveness, providing up to 36 hours of response to sexual stimulation.
Benefits of Cialis:
Usage and Dosage:Cialis should be taken as directed by a healthcare professional. The typical starting dose is 10mg, taken at least 30 minutes before anticipated sexual activity. The dosage may be adjusted based on individual response and tolerability.
Safety:Cialis is generally well-tolerated, but it's essential to follow your healthcare provider's recommendations. Discuss any medical conditions or medications you are taking with your doctor to ensure Cialis is safe and suitable for you.
Consultation:If you have questions or concerns about Cialis or its suitability for your condition, our licensed pharmacists and healthcare professionals are here to provide guidance and support.
Remember, Cialis is a prescription medication, and it's crucial to consult with a healthcare provider before starting any new medication. Our pharmacy is committed to helping you access the right treatment for your needs, promoting a healthier, happier, and more fulfilling life.
How to use:1 tablet before sexual activity once daily. The effect should give the ability for erection for 36 hours. Otherwise refer to physician's prescription
Precautions:Do not take another tablet except after 48 hours pass after the first tablet
pulsesT affects blood flow to the penisThe drug may interact with certain medications, so it's important to tell your healthcare provider about all the medications you are taking.More Information If needed: 1 tablet at bedtime. This option is usually used when taking any other medications.
2 tablets at night.
4 tablets at morning.
5 tablets at dinner.
6 tablets at lunchtime.
7 tablets at dinner.
8 tablets at night.
9 tablets at work.
10 tablets at bedtime.
Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
Show Moreusportsufficiofor pulmonary hypertensionCialis can cause pulmonary hypertension, a serious condition that can affect the heart rhythm. The condition is characterized by a slow, long-lasting decrease in the blood pressure that leads to shortness of breath, lightheadedness, dizziness, and fainting. The most common side effects of Cialis are in the form of rapid worsening of the symptoms below:
Side effects not revealed via medical questionnaire or analysisThis medication can interact with a wide range of medications, including:
It is important to inform your health care provider of all medications and supplements you are taking before starting treatment with Cialis. This includes prescription drugs, over-the-counter medications, and herbal products.
In addition, if you experience blurred vision, double vision, chest pain, or changes in the smell of food or drinking water, contact your health care provider immediately.
SafetyCialis can cause some side effects. The most common are in the form of:
If you have these side effects, seek medical attention immediately.
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